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Patricia A Egner Selected Research

Aflatoxin B1 (Aflatoxin B)

1/2020Aflatoxin B1 exposure and liver cirrhosis in Guatemala: a case-control study.
1/2019Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo as Measured by Liquid Chromatography-Tandem Mass Spectrometry with Isotope Dilution.
1/2017Aflatoxin and viral hepatitis exposures in Guatemala: Molecular biomarkers reveal a unique profile of risk factors in a region of high liver cancer incidence.
8/2015Dietary aflatoxin-induced stunting in a novel rat model: evidence for toxin-induced liver injury and hepatic growth hormone resistance.
3/2015Prenatal exposure of mice to the human liver carcinogen aflatoxin B1 reveals a critical window of susceptibility to genetic change.
8/2012A single neonatal exposure to aflatoxin b1 induces prolonged genetic damage in two loci of mouse liver.
7/2011Aflatoxin B1-DNA adduct formation and mutagenicity in livers of neonatal male and female B6C3F1 mice.
1/2010Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1.
5/2009Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.
9/2006Quantification of aflatoxin-B1-N7-Guanine in human urine by high-performance liquid chromatography and isotope dilution tandem mass spectrometry.
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Patricia A Egner Research Topics

Disease

12Hepatocellular Carcinoma (Hepatoma)
01/2019 - 02/2003
11Neoplasms (Cancer)
01/2021 - 09/2006
10Liver Neoplasms (Liver Cancer)
01/2021 - 08/2002
8Carcinogenesis
01/2013 - 02/2006
6Growth Disorders
01/2021 - 08/2015
4Infections
01/2017 - 08/2002
3Chronic Disease (Chronic Diseases)
01/2018 - 10/2008
3Inflammation (Inflammations)
04/2012 - 02/2006
2Hepatitis B
09/2003 - 02/2003
1Gallstones (Gallstone)
01/2022
1Gallbladder Neoplasms (Gallbladder Cancer)
01/2022
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2020
1Fibrosis (Cirrhosis)
01/2020
1Hepatitis
01/2017
1Squamous Cell Carcinoma of Head and Neck
07/2016
1Mouth Neoplasms (Oral Cancer)
07/2016
1Inborn Genetic Diseases (Disease, Hereditary)
03/2015
1Persistent Infection
10/2013
1Leukemia
08/2008
1Aflatoxin Poisoning
03/2008
1Urinary Bladder Neoplasms (Bladder Cancer)
08/2006
1Body Weight (Weight, Body)
02/2006

Drug/Important Bio-Agent (IBA)

25AflatoxinsIBA
01/2021 - 08/2002
12Aflatoxin B1 (Aflatoxin B)IBA
01/2020 - 02/2003
6Biomarkers (Surrogate Marker)IBA
01/2019 - 02/2003
5DNA AdductsIBA
01/2017 - 02/2003
4CarcinogensIBA
01/2021 - 05/2009
3TriterpenesIBA
07/2014 - 02/2006
3oltiprazIBA
05/2009 - 08/2002
3chlorophyllin (copper chlorophyll)IBA
11/2004 - 08/2002
2MycotoxinsIBA
01/2021 - 01/2017
2DNA (Deoxyribonucleic Acid)IBA
01/2019 - 04/2012
2AlbuminsIBA
01/2018 - 03/2008
2IsothiocyanatesIBA
01/2018 - 10/2008
2sulforaphaneIBA
07/2016 - 01/2013
2MutagensIBA
03/2015 - 07/2011
21- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA
07/2014 - 02/2006
2Proteins (Proteins, Gene)FDA Link
05/2009 - 08/2008
2EnzymesIBA
08/2008 - 07/2005
2ChlorophyllIBA
06/2007 - 02/2003
2Oxidoreductases (Dehydrogenase)IBA
09/2006 - 07/2005
1Coloring Agents (Dyes)IBA
01/2022
1Peroxidase (Myeloperoxidase)IBA
01/2021
1ORALIT (ORS)IBA
01/2020
1GlucosinolatesIBA
01/2018
14-Nitroquinoline-1-oxide (4 Nitroquinoline 1 oxide)IBA
07/2016
1Growth Hormone (Somatotropin)IBA
08/2015
1Oxidants (Oxidizing Agents)IBA
01/2013
1Environmental Pollutants (Pollutants, Environmental)IBA
01/2012
1Hepatitis B Surface Antigens (HBsAg)FDA Link
06/2011
1GuanineIBA
05/2011
1A-Form DNA (A-DNA)IBA
05/2011
1Glutathione Transferase (Glutathione S-Transferase)IBA
01/2010
1AntioxidantsIBA
05/2009
1Schiff Bases (Schiff Base)IBA
05/2009
1AKR7A1IBA
05/2009
1Glutathione (Reduced Glutathione)IBA
10/2008
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
08/2008
1TBE 31IBA
08/2008
1AcidsIBA
03/2008
1Lysine (L-Lysine)FDA Link
03/2008
1NADP (NADPH)IBA
09/2006
1AminesIBA
08/2006
13-ethylanilineIBA
08/2006
1imidazoleIBA
02/2006
1Oleanolic AcidIBA
02/2006
1phenanthreneIBA
11/2005
1HydrocarbonsIBA
11/2005
1NAD (NADH)IBA
07/2005
1quinone (benzoquinone)IBA
07/2005

Therapy/Procedure

4Chemoprevention
08/2008 - 08/2002
1Plant-Based Diet
04/2012
1Drug Therapy (Chemotherapy)
08/2008